A serious collision has closed all lanes of the Fort Erie-bound QEW at Victoria Street in Jordan.
The OPP says a car rear-ended a minivan.
Six people were in the minivan, and one was airlifted to hospital with life-threatening injuries.
The other occupants in the van were taken to local hospitals with non life-threatening injuries. The lone occupant of the car that rear-ended the van also suffered non life-threatening injuries.
Police expect the eastbound lanes to remain closed for several hours.
Westbound lanes are unaffected.