A woman in her 30s suffered life-threatening injuries in one of two serious crashes on Highway 401 early Sunday morning.
The westbound collector lanes near Renforth were completely closed just before 2:30 a.m. after a three car crash left one woman trapped in the back seat of a car.
Reports indicated she was without vital signs as emergency crews responded. She was taken to a nearby trauma centre.
The driver of the second vehicle was not seriously injured.
Police and emergency services were already in the area after another incident about two hours earlier.
A 26-year-old man from Etobicoke is facing impaired driving charges after a two vehicle crash.
The occupants in the other vehicle suffered only minor injuries.