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Jennifer Aniston, Jon Hamm, Rob Lowe, Jennifer Hudson set to Stand Up to Cancer on Sept. 5

Singer Jennifer Hudson performs on NBC's "Today" show on Tuesday, Aug. 19, 2014, in New York. (Photo by Greg Allen/Invision/AP)

LOS ANGELES, Calif. – Jennifer Aniston, Jon Hamm, Halle Berry, Reese Witherspoon and Kiefer Sutherland want to connect with you about cancer.

They are among the stars slated to appear on “Stand Up to Cancer,” the hour-long telethon set to air Sept. 5 on 31 broadcast and cable networks simultaneously.

Other celebrity participants announced Wednesday include Pierce Brosnan, Rob Lowe, Will Ferrell and Ben Stiller. The broadcast will also feature performances by Jennifer Hudson, Ariana Grande, The Who, Common & Lupe Fiasco and Dave Matthews.

Funds raised by “Stand Up to Cancer” support international scientific research aimed at discovering new treatments for various types of cancer. Since its first telethon in 2008, “Stand Up to Cancer” has pledged more than $260 million.