A 48-year-old Mississauga man was killed when the motorcycle he was driving slammed into the rear of a pickup truck on Highway 401 near Highway 427 Saturday afternoon.
The man was pronounced dead on the scene.
A 14-year-old boy was a passenger on the motorcycle. He was airlifted to hospital with serious but non-life-threatening injuries.
The two people in the truck were not hurt.
It happened just after 1:30 p.m.
Eastbound lanes of Highway 401 were closed until just after 6 p.m. while police investigated.
Correction: an earlier version of this story stated the teenaged victim was female.