A 48-year-old Mississauga man was killed when the motorcycle he was driving slammed into the rear of a pickup truck on Highway 401 near Highway 427 Saturday afternoon.

The man was pronounced dead on the scene.

A 14-year-old boy was a passenger on the motorcycle. He was airlifted to hospital with serious but non-life-threatening injuries.

The two people in the truck were not hurt.

It happened just after 1:30 p.m.

Eastbound lanes of Highway 401 were closed until just after 6 p.m. while police investigated.

Correction: an earlier version of this story stated the teenaged victim was female.